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Drug-induced Pulmonary Hypertension Symposium: Applying Lessons Learned from The Aminorex Epidemic


Drug-induced Pulmonary Hypertension Symposium: Applying Lessons Learned from The Aminorex Epidemic Banner

  • Overview
  • Faculty
  • Register
  • Agenda
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Add to Calendar Drug-induced Pulmonary Hypertension Symposium: Applying Lessons Learned from The Aminorex Epidemic 4/13/2023 7:00:00 AM 4/14/2023 1:30:00 PM America/Los_Angeles For More Details: https://stanford.cloud-cme.com/DIPH2023 Description: Pulmonary hypertension (PH) is a rare and fatal cardiopulmonary disease that disproportionately impacts women. Despite the progress in the diagnosis, clinical care, and treatment of PH, unique etiological factors are still being discovered. Iatrogenic forms of PH are one of the leading but under-appreciated causes of the disease in the modern era. This symposium will provide expertise from the following: Stanford Unive... Hoover Institution - David & Joan Traitel Building false MM/DD/YYYY


Date & Location
Thursday, April 13, 2023, 7:00 AM - Friday, April 14, 2023, 1:30 PM, Hoover Institution - David & Joan Traitel Building, Stanford, CA

Overview
Pulmonary hypertension (PH) is a rare and fatal cardiopulmonary disease that disproportionately impacts women. Despite the progress in the diagnosis, clinical care, and treatment of PH, unique etiological factors are still being discovered. Iatrogenic forms of PH are one of the leading but under-appreciated causes of the disease in the modern era. This symposium will provide expertise from the following: Stanford University, international academic centers as well as the broader academic communities, including global organizations (World Health Organization, United States Food and Drug Administration, European Medicines Agency), and stakeholders (patients, industry partners, etc.) to develop a deeper understanding of “drug-induced pulmonary hypertension” and establish pharmacovigilance protocols for monitoring drug safety and rapid identification of PH in at-risk populations.

Registration
There are two ways to attend this hybrid activity: in-person or virtually.

1. In-Person
Registration Fees (Includes course materials, breakfast, lunch, a reception, and a certificate of participation).

Physician/AHP/RN - $399
Pulmonary Vascular Research Institute (PVRI) member from  low income countries - $299 (this registration type will be authenticated through PVRI)
Government Employee - $299
Student - $199
Industry (non-sponsor) - $1,500
Stanford Affiliate (Faculty, Staff, Students, Alumni) - $49

2. Virtually
Registration Fees (Join virtually, via Zoom. Fees include course material and a certificate of participation. You will receive your Zoom link the week of the symposium).

Physician/AHP/RN - $399
Pulmonary Vascular Research Institute (PVRI) member from low income countries - $299 (this registration type will be authenticated through PVRI)
Government Employee - $299
Student - $199
Industry (non-sponsor) - $1,500
Stanford Affiliate (Faculty, Staff, Students, Alumni) - $49


Tuition may be paid by Visa or MasterCard. Your email address is used for critical information, including registration confirmation, evaluation, and certificate. Be sure to include an email address that you check frequently.

STAP-eligible employees can use STAP funds towards the registration fees for this activity.  Complete the STAP Reimbursement Request Form and submit to your department administrator. 

Credits
AMA PRA Category 1 Credits™ (12.25 hours), Non-Physician Participation Credit (12.25 hours)

Target Audience
Specialties - Critical Care & Pulmonology
Professions - Fellow/Resident, Non-Physician, Physician, Student

Objectives
At the conclusion of this activity, learners should be able to:

  1. Consider the various forms of pulmonary hypertension, based on the classifications of the World Health Organization.
  2. Develop skills/strategies to identify at risk patients for pulmonary hypertension.
  3. Identify drug classes and types linked to pulmonary arterial hypertension.
  4. Understand drug-associated mechanisms of toxicity linked to the development of pulmonary arterial hypertension.
  5. Learn pharmacovigilance methods and strategies that can help uncover existing and future pulmonary vascular related drug toxicity.

Accreditation

In support of improving patient care, Stanford Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.  

Credit Designation 
American Medical Association (AMA) 
Stanford Medicine designates this Live Activity for a maximum of 12.25 AMA PRA Category 1 CreditsTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 


Additional Information

Cancellation Policy
Cancellations received in writing no less than 20 days before the course will be refunded, less a 20% administrative fee. No refunds will be made on cancellations received after that date. Please send cancellation requests to [email protected].

Stanford University School of Medicine reserves the right to cancel or postpone this program if necessary; in the event of cancellation, course fees will be fully refunded. We are not responsible for other costs incurred such as non-refundable airline tickets or hotel penalties.

Accessibility Statement
 Stanford University School of Medicine is committed to ensuring that its programs, services, goods and facilities are accessible to individuals with disabilities as specified under Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Amendments Act of 2008.  If you have needs that require special accommodations, including dietary concerns, please contact the CME Conference Coordinator.

Cultural and Linguistic Competency
The planners and speakers of this CME activity have been encouraged to address cultural issues relevant to their topic area for the purpose of complying with California Assembly Bill 1195. Moreover, the Stanford University School of Medicine Multicultural Health Portal contains many useful cultural and linguistic competency tools including culture guides, language access information and pertinent state and federal laws.  You are encouraged to visit the Multicultural Health Portal: https://laneguides.stanford.edu/multicultural-health

For activity related questions, please contact
     Name: Melissa Schwartz
     Title: Events Project Manager
     Email: [email protected]

For CME general questions, please contact 
 
   Email: [email protected]

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Stanford Center for Continuing Medical Education (SCCME) is committed to providing a safe and healthy environment for event attendees and staff members.  SCCME’s decisions and preventive measures will be guided by the requirements and recommendations of Stanford, as well as any federal, state, and local health authorities.  We will continue to monitor the evolving situation and guidelines. 

The responsibility of a safe and healthy environment is shared among SCCME, the venue, and all event attendees.  All attendees are expected to adhere to and abide by the safety measures below, to protect against the spread of COVID-19.

Stanford strongly recommends masking indoors and in crowded outdoor settings.  

Conference Location
Stanford University
Hoover Institution
David & Joan Traitel Building
434 Lasuen Mall
Stanford, CA 94305


Nearby Hotels
View hotel options by visiting: visit.stanford.edu/basics/lodging 

Visiting Stanford
To learn more about traveling to Stanford University, please browse visit.stanford.edu.



Mitigation of Relevant Financial Relationships


Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education.

There are no relevant financial relationships with ACCME-defined ineligible companies for anyone who was in control of the content of this activity, except those listed in the table below. All of the relevant financial relationships listed for these individuals have been mitigated.



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Roham Tahmaseb Zamanian, MD
Associate Professor of Medicine
Stanford University
Course Director, Faculty
Consulting Fee-Merck and Company, Inc.|Consulting Fee-Morphogen-IX|Consulting Fee-GossamerBio|Consulting Fee-Tiakis
Adam Michael Andruska, MD
Clinical Scholar
Stanford University
Faculty
Nothing to disclose
Harm Bogaard, MD
Faculty
Grant or research support-Johnson and Johnson|Grant or research support-Ferrer|Grant or research support-Merck and Company, Inc.|Consulting Fee-Johnson and Johnson (Relationship has ended)|Consulting Fee-Merck and Company, Inc. (Relationship has ended)|Consulting Fee-Novartis AG (Relationship has ended)|Consulting Fee-Ferrer (Relationship has ended)|Consulting Fee-Polarean (Relationship has ended)
Paul Corris, MD
Chairman and Professor
PVRI
United Kingdom
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-Merck and Company, Inc.|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Johnson and Johnson (Relationship has ended)|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Aerovate
Vinicio De Jesus Perez, MD
Associate Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine
Stanford University School of Medicine
Faculty
Nothing to disclose
Peter Dorfmuller, MD, PhD
Consultant
Universitätsklinikum Giessen und Marburg
Germany
Faculty
Nothing to disclose
Pilar Escribano-Subias, MD, PhD
Professor of Medicine
University Hospital 12 de Octubre
Spain
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-Johnson and Johnson|Speakers Bureau-Johnson and Johnson|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Merck and Company, Inc.|Speakers Bureau-Merck and Company, Inc.
Christophe GUIGNABERT, PhD
Director of Research
Université Paris-Saclay
France
Faculty
Nothing to disclose
Anna Hemnes, MD
Professor of Medicine - Allergy, Pulmonary, and Critical Care Medicine
Vanderbilt University Medical Center
Faculty
Consulting Fee-Janssen|Consulting Fee-United Therapeutics|Consulting Fee-GossamerBio|Consulting Fee-Tenax|Stocks or stock options, excluding diversified mutual funds-Tenax
Faculty Photos
Rachel K Hopper, MD
Clinical Associate Professor, Pediatrics - Cardiology
Stanford University School of Medicine, Stanford Medicine Children's Health
Faculty
Nothing to disclose
Charles Khouri, PharmD
Pharmacologist
Grenoble Alpes University Hospital
France
Faculty
Nothing to disclose
Deborah J Levine, MD
Professor of Medicine
Stanford University School of Medicine
Faculty
Nothing to disclose
Raquel Lyn, MD
Fellow
Stanford University
Faculty
Nothing to disclose
David Montani, MD, PhD
Pr
Univ Paris Saclay, APHP, Hopital Bicetre
France
Faculty
Honoraria-Johnson and Johnson|Honoraria-Merck and Company, Inc.|Honoraria-Boehringer Ingelheim Vetmedica GmbH
Marlene Rabinovitch, MD
Dwight and Vera Dunlevie Professor of Pediatric Cardiology
Stanford University School of Medicine
Faculty
Nothing to disclose
Laurent Savale, MD, PhD
Faculty of Medicine
Université Paris-Saclay
France
Faculty
Speakers Bureau-Johnson and Johnson (Relationship has ended)
Steven Shoptaw, PhD
Professor in Family Medicine and Psychiatry and Biobehavioral Sciences
Vice Chair for Research in Family Medicine
UCLA
Faculty
Grant or research support-Alkermes|Grant or research support-Gilead|Grant or research support-Indivior|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Aelis|Advisor-Sparian Biosciences
Olivier Sitbon, MD, PhD
Professor of Respiratory Medicine
Université Paris-Saclay
France
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-Merck and Company, Inc.|Honoraria-Merck and Company, Inc.|Grant or research support-Merck and Company, Inc.|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Gossamer Bio|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Enzyvant|Honoraria-Ferrer|Honoraria-AOP Orphan|Consulting Fee-Johnson and Johnson|Honoraria-Johnson and Johnson|Grant or research support-Johnson and Johnson
Edda Spiekerkoetter, MD
Associate Professor - Pulmonary, Allergy & Critical Care Medicine
Stanford University School of Medicine
Faculty
Nothing to disclose
Yon Sung, MD
Clinical Assistant Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine
Stanford University School of Medicine
Faculty
Nothing to disclose
Andrew Sweatt, MD
Clinical Assistant Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine
Stanford University School of Medicine
Faculty
Nothing to disclose
Yuichi Tamura, MD, PhD
Professor of Cardiology
International University of Health and Welfare
Japan
Faculty
Nothing to disclose
Norbert Voelkel, MD
affiliated Professor
Amsterdam University Medical Centers
Faculty
Nothing to disclose
Hiroshi Watanabe, MD, PhD
Professor, Department of Clinical Pharmacology and Therapeutics
Director of the Clinical Research Center
Hamamatsu University School of Medicine
Japan
Faculty
Nothing to disclose
Jason Weatherald, MD, MS
Associate Professor, Respirologist
University of Alberta
Canada
Faculty
Consulting Fee-Johnson and Johnson (Relationship has ended)|Honoraria-Johnson and Johnson (Relationship has ended)|Consulting Fee-Merck and Company, Inc.|Speakers Bureau-Johnson and Johnson|Independent Contractor (included contracted research)-Merck and Company, Inc.
Qun-Ying Yue, MD
Uppsala Monitoring Centre
Sweden
Faculty
Nothing to disclose
Marc Humbert, MD, PhD
Professor of Respiratory Medicine
Université Paris-Saclay
France
Faculty, Planner
Consulting Fee-Aerovate|Consulting Fee-AOP Orphan|Consulting Fee-Bayer Corporation (Relationship has ended)|Consulting Fee-Johnson and Johnson|Consulting Fee-Merck and Company, Inc.|Consulting Fee-United Therapeutics|Consulting Fee-Tiakis
Meinhard Kneussl, MD
Professor of Respiratory Medicine
Medical University of Vienna
Austria
Faculty, Planner
Other: Travel grant-AOP orphan care
Irene M Lang, MD
Professor, Vascular Biology
Medical University of Vienna
Austria
Faculty, Planner
Grant or research support-AOP-Health|Grant or research support-Actelion-Janssen, MSD|Grant or research support-United Therapeutics|Grant or research support-Medtronic, Inc.|Grant or research support-Neutrolis|Grant or research support-Ferrer
Gérald Simonneau, MD, PhD
Emeritus Professor
Université Paris-Saclay
France
Faculty, Planner
Nothing to disclose

Thursday, April 13, 2023
Registration, Breakfast and Exhibits
7:00AM - 8:00AM
Opening and Welcome
8:00AM - 8:30AM
Roham Tahmaseb Zamanian, MD
Marc Humbert, MD, PhD
Keynote Remarks - Case of Leflunomide & PAH
8:30AM - 9:00AM
Roham Tahmaseb Zamanian, MD
Session 1: Epidemiology of drug and toxin-induced pulmonary hypertension
9:00AM - 10:30AM
Marc Humbert, MD, PhD (Moderator)
Harm Bogaard, MD (Moderator)
WSPH and ESC/ERS guidelines: New Classification of PH Risk Factor
9:00AM - 9:30AM
Gérald Simonneau, MD, PhD
Pharmacovigilance: Capturing a Rare-disease Signal
9:30AM - 10:00AM
Qun-Ying Yue, MD
Identifying New Drugs Associated with PAH
10:00AM - 10:30AM
Charles Khouri, PharmD
Coffee Break and Exhibits
10:30AM - 11:00AM
PAH Associated by Aminorex Fumarate
11:00AM - 11:30AM
Meinhard Kneussl, MD
Session 2: Anorexigen-induced pulmonary hypertension
11:00AM - 2:00PM
Hiroshi Watanabe, MD, PhD (Moderator)
Andrew Sweatt, MD (Moderator)
Meinhard Kneussl, MD (Moderator)
From Fenfluramine to Benfluorex
11:30AM - 12:00PM
Laurent Savale, MD, PhD
Clinical Similarities and Differences with IPAH
12:00PM - 12:30PM
Raquel Lyn, MD
Discussion
12:30PM - 1:00PM
Lunch and Exhibits
1:00PM - 2:00PM
Genetic and Molecular Mechanisms of Meth-APAH
2:00PM - 2:30PM
Vinicio De Jesus Perez, MD
Session 3: Mechanisms of anorexigen-induced pulmonary hypertension
2:00PM - 4:30PM
Marlene Rabinovitch, MD (Moderator)
Christophe GUIGNABERT, PhD (Moderator)
Anna Hemnes, MD (Moderator)
Genetics of PAH and drug-associated PAH
2:30PM - 3:00PM
David Montani, MD, PhD
Anorexigen Associated Pulmonary Vascular Pathology
3:00PM - 3:30PM
Peter Dorfmuller, MD, PhD
Channelopathies and Pulmonary Vascular Disease
3:30PM - 4:00PM
Anna Hemnes, MD
Coffee Break and Exhibits
4:00PM - 4:30PM
Global Epidemic of Amphetamine Abuse
4:30PM - 5:00PM
Steven Shoptaw, PhD
Session 4: Amphetamine-induced cardiopulmonary disease
4:30PM - 6:00PM
Yon Sung, MD (Moderator)
Paul Corris, MD (Moderator)
Deborah J Levine, MD
From Methamphetamines to Prescription Stimulants
5:00PM - 5:30PM
Roham Tahmaseb Zamanian, MD
Discussion and Summary of the Day
5:30PM - 6:00PM
Marlene Rabinovitch, MD
Reception (Non CME)
6:00PM - 7:00PM
Friday, April 14, 2023
Registration, Breakfast and Exhibits
7:00AM - 8:00AM
Cardio-Oncology – A Review
8:00AM - 8:30AM
Irene M Lang, MD
Session 1: Drug & toxin-induced PH – toxic oil and chemotherapeutic substances
8:00AM - 11:00AM
Irene M Lang, MD (Moderator)
Peter Dorfmuller, MD, PhD (Moderator)
Edda Spiekerkoetter, MD (Moderator)
Toxic Oil and Pathomechanisms
8:30AM - 9:00AM
Pilar Escribano-Subias, MD, PhD
Dasatinib-induced PAH and Possible Roles of Other TKI
9:00AM - 9:30AM
Olivier Sitbon, MD, PhD
TKI’s & PAH: Data from the Bench (benefits and risks)
9:30AM - 10:00AM
Christophe GUIGNABERT, PhD
Predicting Safer TKI’s Through Transcriptomics
10:00AM - 10:30AM
Adam Michael Andruska, MD
Agents Inducing PVOD: Alkylating Agents and Solvents
10:30AM - 11:00AM
Marc Humbert, MD, PhD
Discussion
11:00AM - 11:15AM
Coffee Break and Exhibits
11:15AM - 11:30AM
Pediatrics - Diazoxide and PAH
11:30AM - 11:50AM
Rachel K Hopper, MD
Session 2: Drug and toxin-induced pulmonary hypertension – new observations
11:30AM - 1:30PM
Roham Tahmaseb Zamanian, MD (Moderator)
Gérald Simonneau, MD, PhD (Moderator)
Norbert Voelkel, MD (Moderator)
Could Leflunomide and Teriflunomide Induce PAH?
11:50AM - 12:10PM
Jason Weatherald, MD, MS
Chinese herbs and PAH: The Qing Dai Outbreak
12:10PM - 12:30PM
Yuichi Tamura, MD, PhD
Interferon and Direct-acting Antivirals
12:30PM - 12:50PM
Harm Bogaard, MD
Round Table Discussion
12:50PM - 1:15PM
Summary of the Meeting, and Call to Action, Adjourn
1:15PM - 1:30PM
Roham Tahmaseb Zamanian, MD

This CME activity is supported in part by educational grants from Actelion Pharmaceuticals US, Inc., Merck & Co., Inc., & United Therapeutics.

DIPH Stanford Exhibit + Sponsorship Prospectus.pdf

Please review the agreement below, with registration you are agreeing to Stanford's terms and conditions. 
Stanford Medicine Post Graduate Medical Education Sponsorship & Exhibit Agreement.pdf


Contact Us:
Deanna Hudspeth
Stanford University School of Medicine
Palo Alto 49304
Phone: 6507249137
Email: [email protected]

Exhibit at this Event

Exhibitor Packages

Exhibitor Package - Diamond Price: $55000.00
Includes:
  • Recognition as a Diamond Exhibitor Exhibitor
  • One (1) 6’ display table in exhibit area
  • Number of Exhibitor Badges: 4
  • Food/Beverage
  • Exhibit Location: Prime Location

Deadline for order commitment is 3/31/2023 12:00:00 AM.

Exhibitor Package - Gold Price: $45000.00
Includes:
  • Recognition as a Gold Exhibitor Exhibitor
  • One (1) 6’ display table in exhibit area
  • Number of Exhibitor Badges: 3
  • Food/Beverage
  • Exhibit Location: Prime Location

Deadline for order commitment is 3/31/2023 12:00:00 AM.

Exhibitor Package - Platinum Price: $35000.00
Includes:
  • Recognition as a Platinum Exhibitor Exhibitor
  • One (1) 6’ display table in exhibit area
  • Number of Exhibitor Badges: 2
  • Food/Beverage

Deadline for order commitment is 3/31/2023 12:00:00 AM.

Exhibitor Package - Silver Price: $25000.00
Includes:
  • Recognition as a Silver Exhibitor Exhibitor
  • One (1) 6’ display table in exhibit area
  • Number of Exhibitor Badges: 1
  • Food/Beverage

Deadline for order commitment is 3/31/2023 12:00:00 AM.

Exhibitor Package - Sponsor Price: $25000.00
Includes:
  • Recognition as a Sponsor Exhibitor
  • Number of Exhibitor Badges: 1
  • Food/Beverage

Deadline for order commitment is 3/31/2023 12:00:00 AM.

Special thank you to our sponsors and exhibitors: Actelion Pharmaceuticals US, Inc., Aerami Therapeutics, Aerovate Therapeutics, Bayer HealthCare Pharmaceuticals Inc., Boehringer Ingelheim Pharmaceuticals, Inc., Cardiovascular Medical Research and Education Fund (CMREF), CVS Health, Enzyvant Therapeutics, Inc., FLUIDDA Inc., Gossamer Bio Inc., Liquidia, Polarean, Inc., Pulmonary Vascular Research Institute (PVRI), Respira Therapeutics, Reviva Pharmaceuticals, United Therapeutics, & VIVUS. 

 

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