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Targeting the Metabolic Processes of Nonalcoholic Steatohepatitis in Treatment Decisions


Targeting the Metabolic Processes of Nonalcoholic Steatohepatitis in Treatment Decisions Banner

  • Overview
  • Faculty
  • Support
  • Begin


Date & Location
Thursday, December 22, 2022, 12:00 AM - Thursday, December 21, 2023, 11:59 PM

Overview

Internet Enduring Material sponsored by Stanford University School of Medicine. Presented by the Stanford Center for Continuing Medical Education and Med-IQ.

This interactive activity will include three micro-focused modules that present up-to-date science and guidance on the management of NASH. Through text-based summaries, animation, and practical faculty insights, this activity will provide learners with current information on the metabolic processes that contribute to NASH pathophysiology and the latest guidance on the medical management of NASH, including diabetes and obesity therapies that target these metabolic processes.


Registration
     Release Date: December 22, 2022
     Expiration Date: December 21, 2023
     Estimated Time to Complete: ~60 minutes 
     Registration Fee: FREE 

Credits
AMA PRA Category 1 Credits™ (1.00 hours), ACPE Contact Hours (1.00 hours), Non-Physician Participation Credit (1.00 hours)

Target Audience
Specialties - Endocrinology, Diabetes, & Metabolism, Family Medicine & Community Health, Gastroenterology & Hepatology, Internal Medicine
Professions - Fellow/Resident, Non-Physician, Pharmacist, Physician

Objectives
At the conclusion of this activity, learners should be able to:

  1. Recognize the metabolic process that contributes to NASH pathophysiology.
  2. Summarize the latest guidance on the medical and pharmacologic management of NASH.
  3. Identify patients who may benefit from diabetes and obesity pharmacotherapies associated with NASH improvements.

Accreditation

In support of improving patient care, Stanford Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 

Credit Designation 
American Medical Association (AMA) 
Stanford Medicine designates this Enduring Material for a maximum of 1.00 AMA PRA Category 1 CreditsTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

Accreditation Council of Pharmacy Education (ACPE) 
Stanford Medicine designates this knowledge-based activity for a maximum of 1 hour. Credit will be provided to NABP CPE Monitor within 60 days after the activity completion. UAN: JA0000751-0000-22-019-H01-P.


Additional Information

Accessibility Statement
 Stanford University School of Medicine is committed to ensuring that its programs, services, goods and facilities are accessible to individuals with disabilities as specified under Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Amendments Act of 2008.  If you have needs that require special accommodations, please contact the CME office.

Cultural and Linguistic Competency
The planners and speakers of this CME activity have been encouraged to address cultural issues relevant to their topic area for the purpose of complying with California Assembly Bill 1195. Moreover, the Stanford University School of Medicine Multicultural Health Portal contains many useful cultural and linguistic competency tools including culture guides, language access information and pertinent state and federal laws.  You are encouraged to visit the Multicultural Health Portal: https://laneguides.stanford.edu/multicultural-health

Reference List
Please click Reference List to view.

For CME general questions, please contact 
 
   Email: [email protected]



Mitigation of Relevant Financial Relationships


Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education. 

There are no relevant financial relationships with ACCME-defined ineligible companies for anyone who was in control of the content of this activity, except those listed in the table below. All of the relevant financial relationships listed for these individuals have been mitigated.



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Faculty Photos
Aijaz Ahmed, MD
Professor of Medicine - Gastroenterology and Hepatology
Stanford University School of Medicine
Co-Course Director, Faculty
Grant or research support-Intercept
Faculty Photos
Sandy Sallam, PharmD, BCACP, AAHIVP
Clinical Pharmacist
Stanford Healthcare
Co-Course Director, Faculty
Nothing to disclose
Faculty Photos
Nikki Berry
Director, Accreditation
Planner
Nothing to disclose
Faculty Photos
Anne Jacobson, MSPharm, CHCP
Planner
Nothing to disclose
Faculty Photos
Kia Jones, PhD
Med IQ
Planner
Nothing to disclose
Faculty Photos
Rebecca L. Julian, MS
Med-IQ
Planner
Nothing to disclose
Faculty Photos
Larissa Picard-Broussard, BA
CME Coordinator
Med-IQ
Planner
Nothing to disclose
Faculty Photos
Ruth Adewuya, MD
Managing Director
Stanford University
Planner and Reviewer
Nothing to disclose

This activity is supported in part by an educational grant from Novo Nordisk.

INSTRUCTIONS

To receive credit and a certificate, you must complete all of the modules in this activity.

Here are the key takeaways from this activity.
      - NAFLD is the most common type of chronic liver disease in the world, affecting 25% of the global population; of these individuals, approximately 37% develop NASH, the more progressive subtype characterized by inflammation and hepatocyte injury with or without fibrosis
     - Despite advances in the field, certain aspects of the pathophysiology of NAFLD and its progression to NASH remain unclear
     - In 2022, the AACE and AASLD developed joint clinical practice guidelines for the diagnosis and management of NAFLD based on the presence of risk factors for NAFLD and advanced fibrosis or current evidence of advanced liver disease
     - Although no treatments are currently approved by the US FDA for NASH, several therapeutic agents have been shown to have varying degrees of benefit on glycemic control, liver histology, and cardiometabolic risk factors in NASH, including pioglitazone, GLP-1 RAs, SGLT2 inhibitors, and tirzepatide
     - Screening and early intervention for cardiometabolic risk factors—including obesity, hyperlipidemia, and hypertension—are critical for preventing CV events and other extrahepatic complications in patients with NAFLD
     - According to the AGA NAFLD/NASH Clinical Care Pathway, patients with a minimal risk of advanced fibrosis can be managed in the primary care setting with lifestyle interventions such as weight loss, dietary changes, and physical activity
     - High-quality, collaborative patient care, managed by a multidisciplinary team led by a hepatologist who can monitor for disease progression and complications, is essential for patients with a high risk of advanced fibrosis.

MODULE 1 | Metabolic Processes Contributing to NASH Pathophysiology
Time to Complete: 16 minutes
Launch Whiteboard Animation
MODULE 2 | Guidance on Medical Management and Pharmacotherapy for NASH
Time to Complete: 19 minutes
Listen
MODULE 3 | Treatment Decisions for Patients With NASH
Time to Complete: 13 minutes
Listen
POST-TEST QUESTIONS

To redeem credit for this activity, please take a moment to complete the Post-Test. You must answer at least 70% of the questions on this screen correctly to receive credit. Please view results and complete the evaluation for your certificate and credit transcript.

Can’t find the evaluation? Click the MY CE button and select the Evaluation and Certificates tile. Select the Complete Evaluation button associated with the activity.

Reference List

 

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