Stanford Medcast Episode 42: Hot Topics Mini-Series - Gut Microbiome in Multiple Sclerosis

A recent study showed that interaction between the immune system and the gut microbiota plays a crucial role in the development of MS. This episode includes a discussion with Dr. Emmanuelle Waubant regarding her ongoing research and new treatments for multiple sclerosis (MS). Dr. Waubant is the Director of UCSF Regional Pediatric Multiple Sclerosis Center and serves on the clinical care committee of the National Multiple Sclerosis Society's local chapter and the translational research review committee for the society's national office.

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1. Determine how the the gut microbiome has an influence on the immune response in patients with MS.
2. Counsel patients about the importance of a heart healthy diet.

In support of improving patient care, Stanford Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. 

Credit Designation 
American Medical Association (AMA) 
Stanford Medicine designates this Enduring Material for a maximum of 0.50 AMA PRA Category 1 Credits^TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

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References/Bibliography
1.Ochoa-Repáraz, J., Kirby, T. O., & Kasper, L. H. (2018). The Gut Microbiome and Multiple Sclerosis. Cold Spring Harbor perspectives in medicine, 8(6), a029017. https://doi.org/10.1101/cshperspect.a029017
2.Jangi, S., Gandhi, R., et al. Alterations of the human gut microbiome in multiple sclerosis (2016). Nat. Commun. 7:12015. doi: 10.1038/ncomms12015
3.Reynders, T., Devolder, L., Valles-Colomer, M., Van Remoortel, A., Joossens, M., De Keyser, J., Nagels, G., D'hooghe, M., & Raes, J. (2020). Gut microbiome variation is associated to Multiple Sclerosis phenotypic subtypes. Annals of clinical and translational neurology, 7(4), 406–419. https://doi.org/10.1002/acn3.51004
4.Al Bander, Z., Nitert, M. D., Mousa, A., & Naderpoor, N. (2020). The Gut Microbiota and Inflammation: An Overview. International journal of environmental research and public health, 17(20), 7618. https://doi.org/10.3390/ijerph17207618
5.Kohrt, BA, Ojagbemi, A, Luitel, NP, et al. (n.d.). An App-Based WHO Mental Health Guide for Depression Detection: A Cluster Randomized Clinical Trial. JAMA network open. https://pubmed.ncbi.nlm.nih.gov/40408108
6.Holmes-Truscott, E, Litterbach, E, Arampatzi, C, et al. (n.d.). Exploring the social experiences, stigma and discrimination, faced by women with gestational diabetes: A collaborative qualitative study and item-pool development. Diabetic medicine : a journal of the British Diabetic Association. https://pubmed.ncbi.nlm.nih.gov/40407397

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Mitigation of Relevant Financial Relationships

Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education.

There are no relevant financial relationships with ACCME-defined ineligible companies for anyone who was in control of the content of this activity. 

Member Information

Role in activity

Nature of Relationship(s) / Name of Ineligible Company(s)

Ruth Adewuya, MD
Managing Director
Stanford University School of Medicine

Course Director

Nothing to disclose

Emmanuelle Waubant, MD
UCSF

Faculty

Nothing to disclose

Ishita Verma
Student
Stanford University

Planner

Nothing to disclose

This CME Activity is supported in by an educational grant from Novartis Pharmaceuticals Corporation.