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Stanford University 3rd Annual Spinal Muscular Atrophy Continuing Medical Education Conference on Clinical Decision-Making in the Midst of an Unfolding Phenotype (Recorded Sessions)


Stanford University 3rd Annual Spinal Muscular Atrophy Continuing Medical Education Conference on Clinical Decision-Making in the Midst of an Unfolding Phenotype (Recorded Sessions) Banner

  • Overview
  • Faculty
  • Support
  • Begin


Date & Location
Monday, March 14, 2022, 12:00 AM - Thursday, March 13, 2025, 11:59 PM, On Demand

Overview

Internet Enduring Material Sponsored by Stanford University School of Medicine. Presented by the Division of Neuromuscular Medicine at Stanford University School of Medicine. 

Continuing medical education and training is building momentum among the healthcare community treating and managing individuals with SMA.  In this era of disease-modifying treatments, evolving SMA phenotypes are unfolding and clinical decision-making is requiring greater attention for the most optimal outcomes.  Multidisciplinary medical and rehabilitative management recommendations are sought after while weighing the treatment options, long term outcomes, and ethical considerations to effectively treat and manage patients with SMA.  We intend to continue to enhance the knowledge and understanding of healthcare providers including physicians, specialists, physical, occupational, and speech language pathologist and nurses, outside specialized centers, in the clinical decision-making and medical and rehabilitative management of individuals with SMA. 

This recorded series is provided to (1) integrate new 2021 treatment advances into clinical decision-making; and (2) use new SMA standards as a model for public health, primary and multi-disciplinary care of all children and adults with neuromuscular disease. 

This recorded educational lecture series provides an overview of SMA therapeutic treatment updates and clinical decision-making for optimal outcomes, the impact of newborn screening, as well as primary and multi-disciplinary care for children and adults living with SMA.  The didactic videos provide an in depth review of rehabilitation evidence, with a specific focus on multidisciplinary clinical case discussions.  The recordings include clinical decision-making for the evolving phenotypes as well as a shared recorded session to support multi-disciplinary providers to medically manage and develop rehabilitation programs and episodes of care including evaluations, goals, interventions and strategies to exercise.

At the end of this course, participants will have an understanding of the current advances in therapeutic treatments, clinical, and rehabilitative management in SMA. Learners will understand opportunities available to enhance clinical care, determine the most appropriate treatment, medical and rehabilitative interventions, and contemplate the ethical debates to treatment and management.


Registration

Release Date: March 14, 2022
Expiration Date: March 13, 2025
Estimated Time to Complete: 7.25 hours
Registration Fee: FREE 
*Originally recorded on 12/2/2021 - 12/4/2021.


Credits
AMA PRA Category 1 Credits™ (7.25 hours), Non-Physician Participation Credit (7.25 hours)

Target Audience
Specialties - Internal Medicine, Neurology , Pediatrics, Physical Therapy, Speech Language Pathology
Professions - Advance Practice Nurse (APN), Fellow/Resident, Non-Physician, Nurse, Physical Therapist, Physician, Physician Associate, Psychologist, Registered Nurse (RN), Social Worker, Student

Objectives
At the conclusion of this activity, learners should be able to:  

  1. Summarize the advancements and barriers of providing therapeutic treatments for individuals with SMA.
  2. Recognize and discuss the impact of newborn screening, primary, and multi-disciplinary clinical care for children and adults with SMA in this era of evolving phenotypes and therapeutics.
  3. Determine and select suitable rehabilitation programs based on evidence and clinical decision-making for optimal outcomes including standards of care recommendations.

Accreditation

In support of improving patient care, Stanford Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation 
American Medical Association (AMA) 

Stanford Medicine designates this Enduring Material for a maximum of 7.25 AMA PRA Category 1 CreditsTM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 


Additional Information

Accessibility Statement
 Stanford University School of Medicine is committed to ensuring that its programs, services, goods and facilities are accessible to individuals with disabilities as specified under Section 504 of the Rehabilitation Act of 1973 and the Americans with Disabilities Amendments Act of 2008.  If you have needs that require accommodations, please contact the CME Conference Coordinator.

Cultural and Linguistic Competency
The planners and speakers of this CME activity have been encouraged to address cultural issues relevant to their topic area for the purpose of complying with California Assembly Bill 1195. Moreover, the Stanford University School of Medicine Multicultural Health Portal contains many useful cultural and linguistic competency tools including culture guides, language access information and pertinent state and federal laws.  You are encouraged to visit the Multicultural Health Portal: https://laneguides.stanford.edu/multicultural-health

Reference/Bibliography
Click HERE to view a full list of references and resources.  

For activity related questions, please contact
   
 Name: Brandon Armstrong, MHA
     Title: CME Compliance Coordinator
     Ph: (650) 721-2392 
     Email: [email protected]

For CME general questions, please contact 
     Email: [email protected]



Mitigation of Relevant Financial Relationships


Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education.

There are no relevant financial relationships with ACCME-defined ineligible companies for anyone who was in control of the content of this activity, except those listed in the below table. All of the relevant financial relationships listed for these individuals have been mitigated. 



Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Faculty Photos
Ana Tesi Tesi Rocha, MD
Clinical Associate Professor, Pediatric Neurology & Neurological Science
Stanford University Medical Center
Co-Course Director, Faculty
Advisor-Biogen Idec (Relationship has ended)|Advisor-Novartis AG (Relationship has ended)|Honoraria-Roche (Relationship has ended)|Honoraria-Genentech, Inc. (Relationship has ended)|Honoraria-Sarepta (Relationship has ended)
John W Day, MD, PhD
Professor of Neurology and Pediatrics (Genetics) and by courtesy, Pathology
Stanford University Medical Center
Course Director, Faculty
Grant or research support-Audentes|Grant or research support-Biogen|Grant or research support-Cytokinetics|Grant or research support-Ionis Pharmaceuticals|Grant or research support-Novartis Gene Therapies|Grant or research support-Pfizer, Inc.|Grant or research support-Roche|Grant or research support-Sanofi-Genzyme|Grant or research support-Sarepta Therapeutics|Grant or research support-Scholar Rock|Membership on Advisory Committees or Review Panels, Board Membership, etc.-AMO Pharmaceuticals|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Avidity Therapeutics|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Biogen|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Cytokinetics|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Novartis|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Novartis Gene Therapies|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Roche/Genentech Pharmaceuticals|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Sarepta Therapeutics|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Scholar Rock|Consulting Fee-Affinia Therapeutics|Consulting Fee-Audentes Therapeutics|Consulting Fee-Ionis Pharmaceuticals|Consulting Fee-Pfizer, Inc.|Royalties or Patent Beneficiary-Athena Diagnostics
Susan Apkon, MD
Professor, Department of Physical Medicine and Rehabilitation
University of Colorado School of Medicine
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-Sarepta Therapeutics (Relationship has ended)|Grant or research support-Sarepta|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Dyne (Relationship has ended)|Grant or research support-Biogen|Grant or research support-Novartis/AVXS|Grant or research support-Scholar Rock
Diana Castro, MD
Associate Professor, Departments of Pediatrics and Neurology
UT Southwestern Medical Center
Faculty
Advisor-Biogen Idec (Relationship has ended)|Grant or research support-Biogen Idec|Advisor-Novartis AG (Relationship has ended)|Advisor-Roche (Relationship has ended)
Wendy K Chung, MD, PhD
Chief, Division of Clinical Genetics, Department of Pediatrics
Columbia University Irving Medical Center
Faculty
Nothing to disclose
Emma Ciafaloni, MD
Professor of Neurology and Pediatrics
University of Rochester Medical Center
Faculty
Consulting Fee-Biogen Idec (Relationship has ended)|Advisor-Alexion|Honoraria-Ology (Relationship has ended)|Consulting Fee-Sarepta (Relationship has ended)|Honoraria-Amicus (Relationship has ended)|Advisor-Viela
Faculty Photos
Miranda Clements, MS, CCC-SLP
Speech-Language Pathologist
Lucile Packard Children’s Hospital at Stanford
Faculty
Nothing to disclose
Basil Darras, MD
Associate Neurologist-in-Chief; Chief, Division of Clinical Neurology; Director, Neuromuscular Center and Spinal Muscular Atrophy Program, Professor of Neurology
Harvard Medical School
Faculty
Grant or research support-NIH |Grant or research support-National Inst. of Neuro Disorders and Stroke |Grant or research support-Slaney Fund for SMA |Grant or research support-Spinal Muscular Atrophy Foundation|Grant or research support-CureSMA|Grant or research support-Working on Walking Fund |Grant or research support-Ionis Pharmaceuticals Inc. (studies ENDEAR, CHERISH, CS2/CS12 studies|Grant or research support-Biogen for CS11 Study|Grant or research support-AveXis|Grant or research support-Sarepta Pharmaceuticals|Grant or research support-PTC Therapeutics|Grant or research support-Roche|Grant or research support-Scholar Rock |Grant or research support-Fibrogen
Timothy Estilow, OTR/L
Occupational Therapist, Occupational Therapy Department
The Children's Hospital of Philadelphia
Faculty
Speakers Bureau-Sarepta Therapeutics
Faculty Photos
Richard Finkel, MD
Director of Translational Neuroscience Research
St. Jude Children's Research Hospital
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-AveXis (Relationship has ended)|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Biogen Idec|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Capricor (Relationship has ended)|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Catabasis (Relationship has ended)|Royalties or Patent Beneficiary-Children's Hospital of Philadelphia|Royalties or Patent Beneficiary-Elsevier|Advisor-n-Lorem Foundation|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Novartis AG|Membership on Advisory Committees or Review Panels, Board Membership, etc.-ReveraGen|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Roche|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Scholar Rock
Faculty Photos
Tim Hagenacker, MD
Department of Neurology
University Hospital Essen, University of Duisburg-Essen
Germany
Faculty
Advisor-Biogen Idec|Honoraria-Biogen Idec|Grant or research support-Biogen Idec|Advisor-Roche|Honoraria-Roche|Grant or research support-Roche|Grant or research support-Novartis AG|Honoraria-Novartis AG (Relationship has ended)
Kristin Krosschell, DPT
Professor of Physical Therapy and Human Movement Sciences and Pediatrics
Northwestern University Feinberg School of Medicine
Faculty
Advisor-Biogen Idec|Advisor-Genentech, Inc.|Grant or research support-Biogen Idec|Grant or research support-Scholar Rock subcontract via Lurie Children's|Grant or research support-Avexis/Novartis subcontract via Lurie Children's (Relationship has ended)|Consulting Fee-Aspa Therapeutics|Consulting Fee-Cure SMA
Faculty Photos
Katlyn Elizabeth McGrattan, PhD
Assistant Professor, Department of Speech-Language-Hearing Sciences
University of Minnesota
Faculty
Employment-University of Minnesota|Employment-Masonic Children's Hospital|Consulting Fee-Biogen Idec|Consulting Fee-Novartis AG|Consulting Fee-Roche
Nancy Mendelsohn, MD
Senior Vice President Medical Affairs Genetics & Rare Diseases
United Health Group
Faculty
Nothing to disclose
Jacqueline Montes, PT, EdD, NCS
Assistant Professor of Rehabilitation and Regenerative Medicine in the Program for Physical Therapy
Columbia University Irving Medical Center
Faculty
Advisor-Biogen Idec|Consulting Fee-Roche|Advisor-Genentech, Inc.|Advisor-Scholar Rock|Advisor-Sarepta
Meghan Moore Burk, PT, DPT, NCS
Physical Therapist
Department of Physical Therapy, Children’s Hospital Colorado
Faculty
Membership on Advisory Committees or Review Panels, Board Membership, etc.-Genentech, Inc. (Relationship has ended)|Consulting Fee-Biogen Idec
Julie Muccini, Other
Occupational Therapist, Clinical Research Manager, Human Performance Lab
Stanford University
Faculty
Nothing to disclose
Julie Parsons, MD
Professor of Clinical Pediatrics and Neurology
University of Colorado School of Medicine
Faculty
Grant or research support-Biogen Idec|Grant or research support-Novartis AG|Grant or research support-PTC Therapeutics|Grant or research support-Scholar Rock|Advisor-Biogen Idec|Advisor-Scholar Rock|Advisor-Novartis AG
Amy Pasternak, PT, DPT, PCS
Department of Physical Therapy
Boston Children's Hospital
Faculty
Advisor-Roche (Relationship has ended)
Crystal M Proud, MD
Director, Neurology and Director, Neuromuscular Clinic and Spinal Muscular Atrophy Center
Children's Hospital of The King's Daughters (CHKD)
Faculty
Speakers Bureau-Biogen Idec|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Biogen Idec|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Sarepta|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Novartis AG|Membership on Advisory Committees or Review Panels, Board Membership, etc.-F. Hoffmann La Roche Ltd.|Membership on Advisory Committees or Review Panels, Board Membership, etc.-Scholar Rock|Grant or research support-Biogen Idec|Grant or research support-Novartis AG|Grant or research support-AMO|Grant or research support-Astellas|Grant or research support-CSL Behring|Grant or research support-Fibrogen|Grant or research support-PTC|Grant or research support-Pfizer, Inc.|Grant or research support-Sarepta|Grant or research support-Scholar Rock
Faculty Photos
Lee Sanders, MD
Associate Professor of Pediatrics (General Pediatrics) and, by courtesy, or Epidemiology and Population Health
Stanford University
Faculty
Paid consultant-Anthem AI
Perry B Shieh, MD, PhD
Associate Professor of Neurology
UCLA
Faculty
Consulting Fee-Sarepta Therapeutics (Relationship has ended)|Speakers Bureau-Grifols|Speakers Bureau-CSL Behring|Speakers Bureau-Alexion|Speakers Bureau-Catalyst|Speakers Bureau-Genentech, Inc.|Speakers Bureau-Biogen Idec|Consulting Fee-Pfizer, Inc. (Relationship has ended)|Consulting Fee-Novartis AG (Relationship has ended)|Consulting Fee-Biogen Idec (Relationship has ended)|Consulting Fee-Genentech, Inc. (Relationship has ended)|Consulting Fee-Alexion (Relationship has ended)|Grant or research support-Biogen Idec|Grant or research support-Novartis AG|Grant or research support-Sarepta|Grant or research support-Pfizer, Inc.|Grant or research support-Audentes|Grant or research support-Genzyme Corporation|Grant or research support-PTC|Grant or research support-Catalyst|Grant or research support-SOLID Biosciences|Grant or research support-Fulcrum|Grant or research support-AMO Pharm
Charlotte J Sumner, MD
Professor of Neurology, Departments of Neurology and Neuroscience
The Johns Hopkins University School of Medicine
Faculty
Honoraria-Biogen Idec|Consulting Fee-Novartis AG|Consulting Fee-Scholar Rock|Consulting Fee-Epirium|Consulting Fee-GenEdit|Consulting Fee-Atalanta|Consulting Fee-Nura Bio|Grant or research support-Roche|Grant or research support-Biogen Idec|Grant or research support-Argenx|Consulting Fee-Alnylam Pharmaceuticals (Relationship has ended)
Eduardo F Tizzano , MD, PhD
Director
Hospital Universitari Vall d’Hebron, Area Genetica Clinica i Molecular (HUVH), Medicine Genetics Research Group (VHIR)
Spain
Faculty
Advisor-Biogen Idec|Advisor-Novartis AG|Advisor-Roche|Grant or research support-Biogen Idec|Grant or research support-Roche|Consulting Fee-Biogen Idec|Consulting Fee-Novartis AG|Consulting Fee-Roche
Karolina Watson, MS
Nurse Practitioner
Stanford University Medical Center
Faculty
Nothing to disclose
Faculty Photos
Sally Dunaway Young, PT, DPT
Physical Therapist, Clinical Research Manager, Division of Neuromuscular Medicine
Stanford University Medical Center
Faculty, Planner
Advisor-Biogen Idec|Advisor-Roche|Advisor-Scholar Rock|Consulting Fee-Cure SMA|Grant or research support-Cure SMA
Faculty Photos
Tina Duong, PT, PhD
Physical Therapist, Sr. Research Scientist, Division of Neuromuscular Medicine
Stanford University Medical Center
Faculty, Planner
Consulting fees-Roche|Advisory Board-Biogen Idec|Advisory Board-Novartis AG
Richard S Gee, PT
Physical Therapist
Lucile Packard Children’s Hospital at Stanford
Faculty, Planner
Consulting Fee-Biogen Idec|Consulting Fee-Roche
Faculty Photos
Connie Wolford, MSN, FNP-BC
Nurse Practitioner
Stanford University School of Medicine
Faculty, Planner
Speakers Bureau-Biogen Idec|Advisor-Biogen Idec
Dana McDonnell, MS
Clinical Research Coordinator
Stanford University
Planner
Nothing to disclose
Dong Nguyen, MA
Administrative Associate
Stanford University
Planner
Nothing to disclose
Whitney Tang
Clinical Research Coordinator
Stanford University
Planner
Nothing to disclose
Kathie S Lin, MD
Clinical Assistant Professor, Neurology & Neurological Sciences
Stanford University
Reviewer
Nothing to disclose

COMMERCIAL SUPPORT ACKNOWLEDGEMENT
This CME Activity is supported in part by educational grants from Cytokinetics, Inc., Genentech, a member of the Roche Group, Ionis Pharmaceuticals, Inc., Muscular Dystrophy Association, Novartis Gene Therapies, Inc., and Scholar Rock Inc.

Stanford University 3rd Annual Spinal Muscular Atrophy Continuing Medical Education Conference on Clinical Decision-Making in the Midst of an Unfolding Phenotype (Recorded Sessions)
INSTRUCTIONS: Click "LAUNCH YouTube” to begin each presentation. After successful completion of all presentations, please complete the attestation and evaluation for credit(s) to be awarded.  Your credit transcript will be available to view and download immediately in MY CE portal.

Some presentation slides have been modified due to copyright permissions including patient photographs and videos as well as published manuscript graphics. Please refer to citations for missing content.
SMA Welcome & Introductions

Presenters:

John Day & Carolina Tesi-Rocha

Launch YouTube
SMA Treatment Updates

Presenters:

 Crystal Proud & Perry Shieh

Launch YouTube
Weighing Treatment Options

Presenters:

Julie A. Parsons & Richard S. Finkel

Launch YouTube
Long Term Outcomes & Managing Treatment Expectations

Presenters:

Basil Darras & Emma Ciafaloni

 

Launch YouTube
Beyond Motor Assessments: Gaps in Understanding Treatment Impact

Presenters:

Charlotte Sumner & Eduardo Tizzano

Launch YouTube
Population-Based Testing and Newborn Screening: Impact on Referrals and Care

Presenters:

Wendy Chung, Carolina Tesi-Rocha & Diana Castro

Launch YouTube
Goal Centered Approach to Primary & Multi-Disciplinary Care

Presenters:

Karolina Watson & Lee Sanders

Launch YouTube
Transitional Care and Unique Care Considerations for Adults

Presenters:

Connie Wolford & Tim Hagenacker

Launch YouTube
Autonomy to Managing Own Care: Promoting Independence and Caregiving

Presenters:

Susan Apkon & Meghan Moore

Launch YouTube
Provider Panel - Clinical Care Focus

Presenters:

Lee Sanders, Wendy Chung, Tim Hagenacker, Nancy Mendelsohn & Susan Apkon

Launch YouTube
Rehabilitation Evidence Review

Presenters:

Jacqueline Montes & Sally Dunaway Young

Launch YouTube
Musculoskeletal Rehabilitation: Clinical Decision Making and Goals Based on Evolving Phenotype

Presenters:

Tina Duong & Amy Pasternak

Launch YouTube
Rehabilitation Clinical Care Discussions of Atypical/Difficult SMA

Presenters:

Kristin Krosschell, Richard Gee, Tim Estilow, Julie Muccini, Katlyn McGrattan & Miranda Clements

 
Launch YouTube
Claim CME
After you attest to having completed all the course content, you will move onto the course evaluation, and then receive your certificate and/or credit transcript.

 

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