Stanford Medcast Episode 102: Pediatric Pulse Mini-Series: Inside the Epileptic Brain - How Myelin Plasticity Could Change Epilepsy Care

Pediatric epilepsy is a complex condition that affects countless children, but advancements in treatment are paving the way for brighter futures. Join us as Dr. Juliet Knowles, Assistant Professor of Neurology at Stanford University, sheds light on the multifaceted nature of epilepsy in children. In this enlightening discussion, we’ll explore the critical differences between seizures and epilepsy, the profound impact of early intervention on neonatal brain development, and the exciting advancements in genetics that promise to transform treatment options.

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1. Evaluate the advances in how genetics will impact the way epilepsy is diagnosed and treated or cured, in the future.

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American Medical Association (AMA) 
Stanford Medicine designates this Enduring Material for a maximum of 0.50 AMA PRA Category 1 Credits^TM.  Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

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References/Bibliography

1. AANS. (2024, September 10). Epilepsy. American Association of Neurological Surgeons. https://www.aans.org/patients/conditions-treatments/epilepsy/#:~:text=of%20the%20page-,Epilepsy%20is%20a%20disorder%20of%20the%20brain%20characterized%20by%20repeated,impulses%20in%20an%20orderly%20pattern

2. John Hopkins Medicine. (2024, April 29). Seizures and Epilepsy in Children. Johns Hopkins Medicine. https://www.hopkinsmedicine.org/health/conditions-and-diseases/epilepsy/seizures-and-epilepsy-in-children

3. Knowles, J. K., Xu, H., Soane, C., Batra, A., Saucedo, T., Frost, E., Tam, L. T., Fraga, D., Ni, L., Villar, K., Talmi, S., Huguenard, J. R., & Monje, M. (2022). Maladaptive myelination promotes generalized epilepsy progression. Nature Neuroscience, 25(5), 596–606. https://doi.org/10.1038/s41593-022-01052-2

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Mitigation of Relevant Financial Relationships

Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education.

There are no relevant financial relationships with ACCME-defined ineligible companies for anyone who was in control of the content of this activity. 

Member Information

Role in activity

Nature of Relationship(s) / Name of Ineligible Company(s)

Ruth Adewuya, MD
Managing Director
Stanford University

Course Director

Nothing to disclose

Juliet Klasing Knowles, MD, PhD
Stanford University

Faculty

Nothing to disclose

Mary-Tyler Mosley
Medcast Intern

Planner

Nothing to disclose

Lydia Wang
Medcast Intern
Stanford

Planner

Nothing to disclose